Mini- and Microsatellites

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Mini- and microsatellites.

While the faithful transmission of genetic information requires a fidelity and stability of DNA that is involved in translation into proteins, it has become evident that a large part of noncoding DNA is organized in repeated sequences, which often exhibit a pronounced instability and dynamics. This applies both to longer repeated sequences, minisatellites (about 10-100 base pairs), and microsat...

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During the construction of a primary linkage map of the sheep genome, a total of 46,225 parent-offspring transfer of microsatellite alleles were examined through the genotyping of the AgResearch International Mapping Flock. Any observations of mutations were thoroughly rechecked, including examination of new DNA samples, to yield five bona fide mutations from the study. This gave us an observed...

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A proposal for a standardized nomenclature for human leukocyte antigen (HLA) microsatellites is presented. It provides recommendations for Microsatellites as regards to locus name, primer names, and denominations for alleles.

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1997

ISSN: 0091-6765

DOI: 10.2307/3433284